Enhanced surveillance of acute hepatitis B in south-eastern Sydney.
نویسندگان
چکیده
Hepatitis B is a notifiable condition in all Australian states and territories. Medical practitioners and health facilities are required to report episodes of acute disease, while laboratories must notify on positive serological results. In New South Wales laboratories are required to report only the presence of hepatitis B surface antigen (HBsAg). Without clinical information, laboratory reporting of HBsAg fails to distinguish between acute infection and chronic carriage. Since practitioner under reporting is well recognised, surveillance data are likely to underestimate the true incidence of acute clinical infection. Two retrospective reviews of an enhanced surveillance system to improve the identification of acute hepatitis B in south-eastern Sydney are presented. Over a 6-month period, the enhanced surveillance system increased the identification of acute cases by at least threefold. Over a 5-year period, medical practitioners or hospitals reported only 25 per cent of acute disease, the remainder being initially notified by laboratories. Approximately half of the laboratory notifications contained only HBsAg results. The availability of clinical notes, liver enzyme or IgM to core antigen results assisted the public health unit in the identification of possible acute disease. This system of enhanced surveillance has proven to be sustainable, with minimal resources required. We suggest that sentinel enhanced surveillance systems in a sample of New South Wales public health units would be an effective and efficient method to improve the surveillance of acute hepatitis B, and that laboratories be required to report IgM to core antigen, if available, when notifying a positive HBsAg result.
منابع مشابه
Enhanced surveillance of hepatitis B infection in inner-western Sydney.
OBJECTIVES We developed an enhanced surveillance system for hepatitis B to improve the detection of newly acquired cases and to collect epidemiological data. METHODS The study was undertaken from February to June (inclusive) 2005 at the Sydney South West Area Health Service Eastern Zone Public Health Unit. A letter was sent to treating doctors on receipt of a notification, requesting addition...
متن کاملHepatitis A in south-eastern Sydney
The incidence of hepatitis A virus (HAV) in south-eastern Sydney is one of the highest in Australia with large outbreaks previously associated with male-to-male sexual contact. We report HAV notification trends over the period 1 June 1997 to 31 May 1999 for this location. In the first twelve-month period, 233 cases were notified (crude rate 30.5/100,000 per year) with a peak incidence of 110/10...
متن کاملAssessment of the Core Functions of Hepatitis B Surveillance System in the Southeastern Iran: a Qualitative Study
Introduction: Viral hepatitis has been declared as one of the major health problems by World Health Organization. Hepatitis B surveillance system is one of the most important tools for managing the disease and achieving the targets of disease elimination. Despite its high efficiency, hepatitis B surveillance system has always been faced with many challenges. Therefore, the present study aimed t...
متن کاملHepatitis B Virus Surface Antigen Variants Clustered Within Immune Epitopes in Chronic Hepatitis B Carriers from Hormozgan Province, South of Iran
Objective(s) The aim of this study was to characterize the hepatitis B virus surface protein genotypes and sequence variations among hepatitis B virus surface antigen (HBsAg) positive chronic patients in Hormozgan province, south of Iran. Materials and Methods A total of 8 patients enrolled in this study. The surface gene was amplified and directly sequenced. Genotypes and nucleotide/amino a...
متن کاملSentinel surveillance for patients with acute hepatitis in Egypt, 2001-04.
Viral hepatitis is a major problem in Egypt. To define the epidemiology of the disease, sentinel surveillance was established in 5 hospitals in diverse areas of the country in 2001. Data were completed for patients meeting the case definition for viral hepatitis. Of a total of 5909 patients evaluated, 4189 (70.9%) showed positive antibody markers for hepatitis. Out of those, 40.2% had evidence ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Communicable diseases intelligence quarterly report
دوره 28 3 شماره
صفحات -
تاریخ انتشار 2004